Company Details

  • Xi'an Yuanyu Biological Co., Ltd.

  •  [Shaanxi,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , East Europe , Europe , Middle East , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:ISO9001, FDA
  • Description:Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

Xi'an B-Thriving I/E Co.,Ltd.

Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

New product! China wholesale high quality Birch Bark Extract- betulin

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    Payment Type: L/C,T/T,D/P,Money Gram,Western Union
    Terms of Trade: FOB,CIF,FCA
    Min. Order: 1 Kilogram
    Delivery Time: 7 Days

Basic Info

Product Description
Product Name:Birch bark extract
Latin Name:Betula alba L.
Specification:Betulin 80%, 90%, 95%, 98%; HPLC ; Betulinic acid 70%, 80%, 90%, 95%, 98% HPLC
Appearance:Light yellow to white powder
CAS No.:472-15-1/473-98-3
Package:For minimal order: 1KG/Aluminium foil bag, 5 bags in a carton . For large quantity: 25KG/Fiber Drum in net weight; 28KG/Fiber Drum in gross weight (Can be customized)

Betulinic acid is an oxidation product of betulin a traditional medicine product of the triterpene family that is derived from birch tree bark. Previous research characterized it as an effective inhibitor of human melanoma tumor growth through the induction of apoptosis. Other triterpenoid compounds have the same anticarcinogenic and anti-inflammatory effects and are currently being studied in clinical trials for their potential use in treating leukemia.

• Food supplementBirch bark has been shown to act as a laxative and diuretic, and many consume it orally to treat their gout, rheumatism and kidney stones. In fact, one of the plant’s chemical components,Betulinic Acid, is currently being tested as a promising cancer treatment. The water soluble form of the acid inhibited the growth of human prostate cancer cells by nearly 96%,according to a Weill Cornell research team. Some researchers believe that it has the ability to destroy tumor cells and slow the growth of both HIV and melanoma.• CosmeticsWith regards to skincare, it’s often administered as a natural medicinal treatment because it helps facilitate the excretion of fluids and promote metabolic activity. Its anti-inflammatory and skin soothing abilities are often used to treat eczema, psoriasis and warts. Since it conatins vitamins B1, B2, A, C and E, it is also believed

Packaging & Shipping

For minimal order: 1KG/Aluminium foil bag, 5 bags in a carton . For large quantity: 25KG/Fiber Drum in net weight; 28KG/Fiber Drum in gross weight (Can be customized)

Our ServicesCompany Information

Quality Control of Health Sources

1. A system in accordance with GMP standard, supervision on whole production process-
2. Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the detailed Certificate of Analysis
3. Procurement-Strictly on selecting raw materials
4. Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc pharmaceutical and/or food standards
5. Warehousing and storage: Clear and dry condition with suitable temperature.
6.Transportation - Audit and supervise the logistics environment to ensure storage safety
7. Keep samples for all batches goods to be traceable in case of quality discrepance.

What is ISO 9001:2008?
ISO stands for International Standards Organization. The "9001:2008" designation is the specific standard under which our Quality Management System is certified. Since 2003, Wuxi AccoBio Biotech Inc. has successfully implemented a quality system in accordance with the requirements of ISO 9001:2008 quality standard for custom packaging of essential oils, natural cosmetics and their raw materials. We are audited each year to International Standards by Certified auditors. They ensure that our system conforms; specifically we are required to meet the following obligations: Annual Customer Service survey Every customer concern must be logged and trended The Management Team must meet monthly with documented meeting notes All approved vendors must be listed and gone through appropriate screening Internal audits must take place each quarter We must demonstrate objective evidence of improvement We must have written processes and procedures for the following:
•Defining Management Responsibilities
•Defining Training requirements and responsibilities
•Establishing and Evaluating Quality Vendors
•Control of Product
•Control of Non-conforming product
•Production planning
•Calibration and testing of equipment
•Inspection and acceptance criteria
•Purchasing and receiving
•Identify business elements that can affect quality
•Documentation and record keeping
•Master list of approved forms
•Traceability from purchase through to end user
•Verification and storage of product
•Effective handling and packaging
•Analysis of data
Pleaseclick hereto download a copy of our ISO 9001:2008 registration.
What is an MSDS?
MSDS stands for Material Safety Data Sheet. It provides detailed product information needed by material handlers and emergency workers on physical and chemical data. This includes melting points, boiling points, flash points, reactivity, first aid instruction, toxicity, storage recommendations, disposal instructions, control measures, protective equipment instructions, and spill and leak procedures.
What is a Certificate of Analysis?
A Certificate of Analysis is the result of testing against acceptable parameters. Certificates of Analysis can look quite different from product to product, industry to industry. However, with Essential Oils, measurement quite often consists of the dominant constituent of a particular oil.
Quality Assurance

Quality Assurance laboratory is well designed as per pharma standards having chemical and microbiological sections, apart from instrumentation room. All sections have latest testing instruments, which are handled by qualified and experience technical personnel assuring the quality of in put raw material and final products as per laid down specifications. In process control ( IPC ) tests are carried out at specified stage of processes to conform that quality standards are met .AccoBio Quality Assurance team monitors the quality of the products right from the raw materials procurement stage to the expiry date of the finished product, thus ensuring the customers get the finest products.In order to insure the quality,AccoBio control raw material strictly. All the products should be record with all the procedure so that we can check each step easily.
Lab equipment:
• HPLC
• ECD-GC
• UV-VIS Spectrophotometer

Equipment introduction:
• 4 sets of 6 M3 multifunctional stainless extracting tank
• 4 sets of 1.5MT stainless external reflux combination
• 1 set of 2.4MT dual-action falling-film evaporator
• 4 sets of glass lining reaction vessel
• 6 sets of 350*1500 PE chromatographic column
• 250 vertical spray drying tower
Productionprocedure is according to GMP standard strictly to ensure the uniformity and stability of our products.

Introduction

"Introduction:      
    Birch bark has been shown to act as a laxative and diuretic, and many consume it orally to treat their gout, rheumatism and kidney stones. In fact, one of the plant’s chemical components, Betulinic acid, is currently being tested as a promising cancer treatment. The water soluble form of the acid inhibited the growth of human prostate cancer cells by nearly 96%, according to a Weill Cornell research team. Some researchers believe that it has the ability to destroy tumor cells and slow the growth of both HIV and melanoma.
 
    The birch bark extract is a healing extract, which for centuries was used in treatment and in a life; it is organic, balanced natural combination of various curative natural connections - Betuline, Betulinic acid, Lupeol, etc.
 

   Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name.It is manufactured from raw matertial betulin by chemical synthesis. Betulinic acid has the anti-inflammatory, anti-virus, anti-tumor,cholagogic function and liver protective effect.It can also promote human body metabolism. As a kind of biologics, betulinic acid has the curative effect in anti-HIV, cancer and human melanoma cell without killing healthy cells. According to the recent research, it has the inhibiting effect on cerebroma,neuroectodermal tumor, leukemia and other malignant cells."


Active ingredients

"Natural Compounds

Catalog Number473-98-3

The birch bark extract is extracted from the bark of birch. The main active ingredient is betulin. It has the functions of anti-inflammatory, anti-virus, inhibiting the dissolution of protein in hair fiber, improving damaged hair and promoting hair growth. It can be applied to food, Cosmetics and pharmaceutical industries


Specification

Specifications

Type:White Birch Extract

Form:Powder

Part:Bark

Extraction Type:Solvent Extraction

Packaging:Drum, Plastic Container, Vacuum Packed

Place of Origin:Zhejiang, China (Mainland)

Grade:First Grade

Brand Name:Boten

Model Number:BT-WBE

Latin Name:Betula platyphylla

Active Ingredients:Betulin/Betulinic acid

Color:White powder

Appearance:Fine Powder

Odor:Characteristic

Size:100% pass 80 mesh

Specification:Betulin 80%,90%,98% Betulinic acid 50%,90%,95%,98%

Test Method:HPLC

Sample:Free Sample

Shelf life:2 Years


Extraction Process

500g of dry birch (ifeiw / a P IatyphyI la Suk) bark was extracted with 5 times of 80% methanol and refluxed for 3 times. Each time the mixture was refluxed for 60min, the extracts were combined and the methanol was recovered Liquid, into the step-open container placed in the heating volatile methanol, let cool, add I times the amount of water, the precipitation of a large number of precipitates, extract the concentrate by suction; concentrate with 2 times the amount of water transferred into suspension, I times the amount of methylene chloride extraction 3 times, the combined extract, vacuum recovery of methylene chloride concentration, to more difficult to concentrate, placed in an open container heating as much as possible to play Nini methyl chloride, let cool, dry; After 200-300 mesh silica gel column chromatography, first with 1-2 times the amount of hexane as the mobile phase elution, followed by 3-5 times the amount of methylene chloride and methanol 10: 1 elution ratio elution, The eluate was collected, concentrated under reduced pressure at room temperature, and dried to obtain 37. 2 g of the extract of the present invention. The content of lupeol in the inventive extract was 22.18% by HPLC.


Faq

Q1: What's the main order for the usual?

  For the hight value product min order starts from 1g and generally starts from 10g.

 

Q2: What's  the sample cost?

  Generally free sample could be oferred except the high value product.

 

Q3: What's the package and payment terms?

  Our package:  in 2 plastic bags, Aluminum foil bag outside, 1-10kg /carton, 10-25kg /drum.

  Payment: T/T, L/C, could be through Paypal, Escrow, West  Union.