Xi'an Yuanyu Biological Co., Ltd.
Mangosteen Extract Xanthones 40% UV
1. specifications: xanthones 40% UV
2. appearance:brown fine powder
Mangosteen, also known as the Queen of Fruits, is a delicious tasting fruit native
to Southeast Asia. Mangosteen rind was found to have strong antioxidant properties,
due to the high content of Xanthones. Of the 200 known xanthones, nearly 50 are
found in the "Queen of Fruits”. α-, β-, γ-mangostin are the major components, the
most abundant of which is α-mangostin，(NSAID) class of anti-inflammatory drugs, of which NSAIDS drugs have many side effects, common for the bleeding of the stomach, liver damage, etc., of which Nimesulide (NSAID) class of anti-inflammatory drugs, (NSAIDS drugs), there are many clinical reports that long-term use will lead to adverse reactions such as liver function occurred, and has been shelved in Ireland.
Mangosteen extract for arthritis, rheumatoid arthritis long-term use of anti-inflammatory drugs in patients can be said to be a new choice, mangosteen extract to mangosteen, 100% natural ingredients, no side effects of doubt, and by clinical trials Data show that the effect of drugs and quite can be used as usual health care products.
The fragrance of mangosteen is mainly composed of volatile components, including hexyl acetate, leaf alcohol (cis-3-hexenol) and α-Cuban (Copaene). Among them, a kind of α-tanshinone has significant antioxidant activity and has anti-inflammatory and antibacterial effect.
There are antibacterial, antifungal, protein kinase inhibitors
Inhibition of myosin kinase and Camp-dependent protein kinase in rat liver.
, Anti-HIV protease
IC50 was 5.12μM, which decreased the transport of Ca2 + -ATPase and Ca2 + in skeletal muscle sarcoplasmic reticulum in a dose-dependent manner.
Purity: HPLC & gt; 98%
Molecular weight: 410.59 g / mol
Molecular formula: C24H26O6
Form:Powder, Brown powder
Extraction Type:Solvent Extraction
Packaging:Carton, aluminiu foil bag inside
Place of Origin:Shaanxi, China (Mainland), Shaanxi,China(Mainland)
Model Number:Monomer plant
Shelf life:2 Years
Mangosteen extract Garcinia angustifolia Mangosteen as the raw material extraction active ingredients, containing xanthones, phenolic acids, anthocyanins, polymer tannic acid and other ingredients. Has good antioxidant activity, antibacterial, anti-inflammatory and anti-allergy effect
The fresh mangosteen peel was dried and pulverized 6.4 kg, and then extracted with 95% ethanol 3 times for 2 hours, and the combined extract was concentrated under reduced pressure to obtain mangosteen peel extract.
854g fresh mangosteen pulp was extracted with 95% ethanol, then distilled water was extracted 3 times, each time for 2h, then distilled water was extracted and concentrated under reduced pressure to obtain mangosteen pulp extract.
1. What inhibitors of bacteria can be inhibited?
Mangosteen extract on the nature of a variety of pathogenic microorganisms have a strong inhibitory effect. Can inhibit the dermatology common pathogens - Staphylococcus aureus growth, some of which components of methicillin-resistant Staphylococcus aureus also has an inhibitory effect. Mangosteen polysaccharide extract can stimulate phagocytic cells to kill intestinal bacteria Salmonella intracellular bacteria, stimulating white blood cells play a phagocytic, bactericidal effect.
2. Is there an anti-allergy effect?
The anti-inflammatory activities of the two flavonoids extracted from mangosteen, α, γ-tumbling elements, can significantly inhibit the nitric oxide production of the RAW264.7 cell line stimulated by lipopolysaccharide and dinoprostone Products and nitric oxide synthase expression. It has been suggested that the reduction of dinoprostone levels by both substances is achieved primarily by inhibition of cyclooxygenase 2 activity and nitric oxide production. In the model of paw edema induced by carrageenan injection, the inhibitory effect was found after treatment with α-tramadol for 3 hours. Γ-down twist son can inhibit the synthesis of prostaglandin nerve cells in rats. Therefore, these two substances have a good anti-inflammatory effect, can be used as anti-inflammatory drug development of precursor compounds. Studies have shown that 40% ethanol extract on immunoglobulin E-mediated RBL-2H3 cells have a strong inhibitory effect on histamine release. In addition, the passive skin allergic reaction was also significantly inhibited, indicating mangosteen extract has good anti-histamine and anti-allergic skin
3. Whether the role of cancer cells?
Mangosteen extract also enhance the body's immune function, and a variety of human tumor proliferation has a good inhibitory effect. Mangosteen polysaccharide has a phagocytic cell-like intracellular killing activity, involved in human immune function. Garcinia flavonoids E has strong cytotoxic effects on various liver cancer cell lines, as well as a number of gastric cancer and lung cancer cell lines.