Indian Bread Extract / Poria cocos mushroom Polysaccharides supplier,factory,price

Company Details

  • Xi'an Yuanyu Biological Co., Ltd.

  •  [Shaanxi,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , East Europe , Europe , Middle East , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:ISO9001, FDA
  • Description:Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

Xi'an B-Thriving I/E Co.,Ltd.

Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

Indian Bread Extract / Poria cocos mushroom Polysaccharides

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    Payment Type: L/C,T/T,D/P,Money Gram,Western Union
    Terms of Trade: FOB,CIF,FCA
    Min. Order: 1 Kilogram
    Delivery Time: 7 Days

Basic Info

Product Description

Product information

English Name: Poria cocos mushroom Polysaccharides
Latin Name: Poria cocos (Schw.) Wolf
Specs: 30%-50% Polysaccharide by UV
Part Used: Dry sclerotia
Solubility: Well soluble in water Action:
To dispel wind-heat,to prmote eruption,and to cause diuresis.

Main Function:
1) Anti-cancer, owning the strong suppression to transplantable cancer of growth retardation;
2) Anti-inflammatory and anti-viral, it will ease the side-effects of chemotherapy and radiation treatment, cure hronic hepatitis and delay aging;
3) Poria cocos polysaccharide can enhance the cytotoxicity of T lymphocyte, that is to say, it will strengthen cellular immune response.

Application:
1) Applied in health product field, as raw material to produce various kinds of health products, such as poria cocos polysaccharide capsule, tablet, electuary and so on;
2) Applied in pharmaceutical field, oral pachymaran is a kind of common medicine to treat tumour.
3) Applied in cosmetic field, as raw material to added into cosmetic, which can delay skin aging.

Packaging & Shipping

Storage Situation
Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat.
Shelf Life
Two years under well Storage situation and stored away from direct sun light.
Package
Cardboard barrels and two plastic-bags inside, 25Kg each net.

ShippingTNT.UPS. DHL.by sea. by plane. T/T. L/C.West Union. Money Gram and other.Company Information

why choose us

Shaanxi Sciphar Hi-tech Industry Co., Ltd. ("Sciphar") is a global health industry manufacturers and suppliers of raw materials. The company spirit of "honesty, innovation first, practical-based" business philosophy, effective and practical management team in the development of the company to lay a solid foundation and also gradually create "Sciphar" as a brand for the industry leader.

1.We will offer you COA.MSDS.ISO.KOSHER.HALAL certification

2.our products

3.our storage.factory.team and exhibition

FAQ

Q1:Are you a manufacturer or trading company?

A1: Our company has 8 years experiences in producingPlant Extracts, but we also do trading business.

Q2:What's your MOQ( Minimum Order Quantity )?

A2: Our MOQ is different in each product, and following the buyer's type.

Q3:What's your delivery time?

A3: Usually we produce within 3-5 working days after receiving the payment, and shipping time for express is about 2-3 days depends on destination.

Q4:What about the shipping methods?

A4: For urgent order and light weight, you can choose the following express: UPS, FedEx,DHL, EMS. For heavy weight, you can choose to deliver the goods by air or by sea to save cost.

Q5:What about the payment methods?

A5: We accept T/T, L/C for big amount, and for small amount, you can pay us by paypal, Westeunion.

Our Servicesfor more information. wamrly welcome to contact us as follows :

contact person: Mr Lu

phone number: 00-86-13893322639

email address: info(at)westfesi.com

pls click the following "send". thank you!

Introduction

Poria (Indian Buead,Tuckahoe)


Poria cocosis a polypore fungus parasitic on roots or saprophytic on rotten stumps of certain pine trees growing in loose sandy soil, the most common including Pinus massoniana Lamb, P. densiflora Sieb. et Zucc., P. yunnanensis Franch., P. taiwanensis Hayata, and P. thunbergii Parl.


Action:To cause diuresis, to invigorate the spleen function and to calm the mind.


Process


Tuckahoe ——washed by water——drying —fines(40 mesh)—— extracted by 10 fold 


Alcohols——centrifugation——concentration——purified ——atomized drying —— grades——packs—— Detection of physicochemical index——put in storage


Active ingredients

Poria Mushroom:Phytochemicals and Constituents.

 Main Constituents:Pachymaran(CAS.65637-98-1):recomposed from Beta-pachyman(CAS.9037-88-1),C6H10O5. 


 Poria Cocos Poria Mushroom Hoelen. Other Phytochemicals:Beta-pachyman;adenine;several organic acids such as pachymic acid,caprylic acid;dodecenoic acid;pachymic acid;palmitic acid;piaicolic acid;tumulosic acid;ergoterol;eburicoic acid;histidine acid;Trametenolic acid; Dehydroeburicoic acid; Poricoic acid;3-beta-hydroxylanosta-7,9(11),24-trien-21-oic acid;poriatin;ganoderic acid.chitin, protein, fat, glucose, sterols, lecithin, gum, choline,b-amyrin acetate; Pachyman; Pachymaran; Glucan H11; Ergosterol; Caprylic acid; Undecanoic acid; Lauroic acid; Dodecenoic acid; Palmitic acid; Dodecenoate; Caprylate; Fumulosic acid methylester; Polyporenic acid C methylester; Pachymic acid methylester; 7, 9 (11)-dehydropachymic acid; 7, 9 (11)-dehydropachymic acid methylester; 3b-hydroxy-lanosta-7, 9 (11), 24-trein-21-oic acid; 3b-hydroxy-16a-acetyloxylanosta-7, 9 (11), 24-trien-21-oic acid; 3b-,16a-dihydroxylanosta-7, 9 (11), 24 (31)-trien-21-oic acid methylester. 


 The primary constituent of hoelen is fiber; it is in the form of beta-glucan (chains of sugar, mostly glucose; a polysaccharide), called pachyman. This component makes up 91~98% of the dried fungal mass, most of it being an insoluble fiber; there is virtually no lipid (less than 0.15%) and little protein. To make decoctions, the mushroom mass is sliced very thin (see photo). When cooked in water to make an herbal tea, most of the insoluble fiber is left behind (though some becomes suspended by the boiling process), and virtually all the soluble fiber enters the water, forming a somewhat cloudy material. 


 The herbal classics CHMM(Chinese Herbal Materia Medica) noted the herb Sclerotium contains various constituents: "①Triterpenes:pachymic acid,tumulosic acid,[3beta-hydroxylanosta-7.9(11),24-TCMLIBien-21-oic acid],pachymic acid methyl ester,tumulosic acid methyl ester,[7,9(11)-dehydropachymic acid methyl ester],[3beta,16alpha-dihydrox-ylanosta-7,9(11),24(31)-TCMLIBien-21-oic acid methyl ester],polypenic acid C methyl ester,TCMLIBametenloic acid,eburicoic acid,dehy-droeburicoic acid,poricoic acid A、B、C、D、DM、AM;[3beta-hydroxy-16α-acetylosy-lanosta-7,9(11),24-TCMLIBien-21-oic acid],[7,9(11)-dehydropachymic acid]. 


 ②Polysaccharides:pachy-man,Pachymaran,and higg(1,3),(1,6) branch beta-D-gluan H11.Other include ergo-sterol,caprylic aid,undecanoic,lauric acid,dodecenoic acid,palmitic acid,dodecenoate,caprylate."(2) 


 Poria Cocos Poria Mushroom Hoelen. There is conflicting information about the possible immunological effect of the beta-glucan from hoelen; most of the information suggests that it is of low activity. Some other mushrooms of the Polyporaceae, including both of the Grifola species mentioned above, contain immunologically active beta-glucans that have been developed into medicinal products by extracting and concentrating the high-molecular weight components.But with hoelen, there has been little work done on isolating an active polysaccharide fraction for medicinal use. In fact, most efforts with the material are towards developing potentially useful dietary fibers that may promote, rather than impair, mineral absorption. 


 The mushroom also contains several triterpene acids, including pachymic acid (structure image, left), tumulosic acid, eburicoic acid (a component of many mushrooms,Chemical name:3 beta-hydroxy-24-methylene-8-lanostene-21-oic acid;Cas No:560-66-7), and poricoic acid.Some of these are actively being researched for potential medicinal uses, including anticancer effects seen in laboratory studies (used in amounts far higher than one would usually get from the crude herb).These triterpenes may have some immunological effects as well, though far more research into such pharmacological activity has been done on other mushrooms, especially Ganoderma lucidum, which has a higher concentration of triterpenes (called ganoderic acids). To study these compounds, alcoholic extracts are made, which leave behind the polysaccharides. 

Up. 


 The glucans may have a soothing effect on the stomach and intestines, which can explain the role of hoelen in formulas that treat nausea, vomiting, diarrhea, loss of appetite, stomachache, and stomach ulcer, as well as cases of excess phlegm production that may result from stomach irritation. This effect will be stronger in decoctions than with the pills because of the higher dosage involved, but even the lower dosages may have an effect due to direct contact of the herb constitutents with the stomach and upper portion of the intestines. 


 Poria Cocos Poria Mushroom Hoelen. The triterpenes may be responsible for other claimed effects, such as diuretic activity; hoelen is often combined with alisma (zexie), which also has triterpenes and is considered a diuretic.In addition, these compounds can also have a benefit for the digestive system. The amount of the trite


Specification

Specifications

Type:Herbal Extract

Variety:Poria Cocos Extract

Form:Powder

Part:Dry sclerotia

Extraction Type:Solvent Extraction

Packaging:Drum, Vacuum Packed, Carton

Place of Origin:Heilongjiang, China (Mainland)

Grade:TOP

The Latin Name:Poria cocos (Schw.) Wolf

Botanical Sources:Dry sclerotia

Active Ingredient:Polysaccharide

Application dosage form:Capsules or pills or others

Assay:20% Polysaccharide

Export countries:USA.Japan and European countries

Solvent extration:Ethanol

Packing:Cardboard drum or carton

Certificate:HACCP,ISO9001, Halal,CIQ,PONY,GMP,etc

Mesh:100mesh



Extraction Process

Glycoside reference substance placed in 50mL volumetric flask, with 50% methanol volume to the scale, the concentration of 1.025mg / mL of astilbin reference substance stock solution. 2.2


Preparation of ethanol extract of Smilax glabra Pieces of Chinese medicine smashed Poria cocos powder 5g, 8 times the amount of 70% ethanol, 85 ℃ into a meal,


Water bath on the reflux extraction 2 times, each 1h, filtration, combined filtrate, add ethanol, said to take soil Fuling coarse powder 5g, plus 8 times the amount of water, boiled in 85 ℃ electric boiling 2 times, each 1h, filter , Together


To 100 mL, as an alcohol extraction solution. 2.3 soil Fuling water extract preparation


And the filtrate, add water to volume to 100mL, as water extraction solution. 3 animal model


36 ICR mice were fasted for 12 hours and randomly divided into 4 groups: blank control group, model group, Smilax glabra ethanol extract group and Smilax glabra aqueous extract group.

(0.1 mL / 10 g) and 2 mg / mL Smilax glabra extract (the dosage is 2 mg / mL), the extract of Smilax glabra and the extract of Smilax glabra 0.1 mL / 10 g). 4


Determination of serum uric acid in experimental animals to take the whole mouse blood 0.5mL, 37 ℃ water bath 20min, 3700r / min centrifugation 10min. Take 100μL of serum in centrifuge tube, add 900μL chromatographic methanol, 10000r / min centrifugation 10min, vortex mixing, take the supernatant 400μL, add 400μL 0.2% acetic acid water, vortex mixing,


Normalized purity of 97.5%); uric acid reference substance (Sigma and glycosides (homemade,


037K0694 purity of 99%); methanol for chromatography pure; acetic acid for the Department of Analysis,


Pure; acetonitrile for chromatography pure; potassium oxonate (Sigma, purity of 97%)


Faq

Q: long-term use of tuckahoe polysaccharides affect it? Direct use of Poria can?

A: Poria is a traditional Chinese medicine, suitable for long-term use, made of Poria polysaccharides can be assured that the use will not produce side effects. Poria polysaccharide is Poria extract, with anti-cancer effect, compared to Poria effect is more obvious, more easily absorbed, you want to play a good effect or recommend the use of Poria polysaccharide, usually can also use Poria soup to drink, health.

Q:What is the role of Poria?

A:1. Diuretic effect: 25% tuckahoe alcohol infusion to the normal rabbit intraperitoneal injection of 0.5g / Kg, there diuretic effect. With the removal of adrenal gland in rats that diuretic effect and the absorption of tubular Na +. In this case,

2. Antitumor effect: Poria polysaccharides on mouse sarcoma S180 inhibitory effect, inhibition rate of 96.88%. Fuling polysaccharide F1 and H11 could be extracted from the mycelium of Poria cocos, which had obvious anti-tumor activity.

3. Immunopotentiation effect: Poria polysaccharide on normal and tumor-bearing mice have enhanced immune function, can enhance the phagocytic function of mouse macrophages. 

4. Poria water, ethanol, ether extract on isolated frog heart are enhanced contraction, speed up the heart rate. In this case,

5. Decoction, especially Fu Shen injection, the sedative effect on animals.