Company Details

  • Xi'an Yuanyu Biological Co., Ltd.

  •  [Shaanxi,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , East Europe , Europe , Middle East , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:ISO9001, FDA
  • Description:Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

Xi'an B-Thriving I/E Co.,Ltd.

Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

GMP Hot Sale Mangosteen Extract 10%-30% Polyphenols 5%-95% Mangostin

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    Payment Type: L/C,T/T,D/P,Money Gram,Western Union
    Terms of Trade: FOB,CIF,FCA
    Min. Order: 1 Kilogram
    Delivery Time: 7 Days

Basic Info

GMP Hot Sale 5%-95% Mangostin Mangosteen Extract

1.The Introdution of Mangosteen Extract

Mangosteen, known as the Queen of Fruits, is a tasty fruit native to Southeast Asia. Having similar size as tangerine, the ripe mangosteen has a smooth, dark purple rind holding snow-white fruits inside. Mangosteen rind was found to have strong antioxidant activity, due to the presence of high content of prenylated xanthone derivatives.

2.Product Details

Specification of Manosteen Extract

Botanical Source:

Garcinia mangonstana L.

Part used:

Seed

Specification:

Flavone 6%

Item

SPECIFICATION

Description:

Appearance

Yellow-Brown Powder

Flavor & Odor

Characteristic

Particle size

100% pass 80 mesh

Physical:

Loss on Drying

≤5.0%

Bulk density

40-60g/100ml

Sulphated Ash

≤5.0%

GMO

Free

General Status

Non-irradiated

Chemical:

Pb

≤3mg/kg

As

≤1mg/kg

Hg

≤0.1mg/kg

Cd

≤1mg/kg

Assay:

Ursolic acid

≥20%

Microbial:

Total microbacterial count

≤1000cfu/g

Yeast & Mold

≤100cfu/g

E.Coli

Negative

Staphylococcus aureus

Negative

Salmonella

Negative

Enterobacteriaceaes

Negative

3.Packing&Storage

Package:Doubleplasticbaginside,aluminumfoilbagorfiberdrumoutside.

Delivery Detail:Within one week

Storage:Storedinaclean,cool,dryarea;keepawayfromstrong,directlight.

ShelfLife:Twoyearswhenproperlystored.

4.Main Function

  • Mangostin is a kind of xanthones able to scavenge free radicals, a high ranker on the ORAC antioxidant scale. Remarkable antioxidant activity superior than Vitamins and abilities of anti-inflammatory, anti-tumor, anti-malaria and phytoestrogen effect and antimicrobial activity against fungi or bacteria.
  • Mangostin is used to treat skin infections, wounds,and diarrhea. Alpha-mangostin, a xanthone, inhibited growth of human leukemia HL60 cells, reduced the synthesis of prostaglandins, and prevented oxidative damage of LDL in vitro.
  • There is also preliminary evidence that alpha- and gamma-mangostins act as histamine and serotonin receptor blockers, and also inhibit HIV-1 protease. Garcinone E, another xanthone, exerts cytotoxic effects against human hepatocellular carcinoma cells. Extract from the pericarp of mangosteen has antiproliferative, antioxidative, and apoptotic effects against human breast cancer

Introduction

Mangosteen, also known as the Queen of Fruits, is a delicious tasting fruit native

to Southeast Asia. Mangosteen rind was found to have strong antioxidant properties,

due to the high content of Xanthones. Of the 200 known xanthones, nearly 50 are

found in the "Queen of Fruits”. α-, β-, γ-mangostin are the major components, the

most abundant of which is α-mangostin,(NSAID) class of anti-inflammatory drugs, of which NSAIDS drugs have many side effects, common for the bleeding of the stomach, liver damage, etc., of which Nimesulide (NSAID) class of anti-inflammatory drugs, (NSAIDS drugs), there are many clinical reports that long-term use will lead to adverse reactions such as liver function occurred, and has been shelved in Ireland.

Mangosteen extract for arthritis, rheumatoid arthritis long-term use of anti-inflammatory drugs in patients can be said to be a new choice, mangosteen extract to mangosteen, 100% natural ingredients, no side effects of doubt, and by clinical trials Data show that the effect of drugs and quite can be used as usual health care products.



Active ingredients

The fragrance of mangosteen is mainly composed of volatile components, including hexyl acetate, leaf alcohol (cis-3-hexenol) and α-Cuban (Copaene). Among them, a kind of α-tanshinone has significant antioxidant activity and has anti-inflammatory and antibacterial effect.

Α-inverted twist

There are antibacterial, antifungal, protein kinase inhibitors

Inhibition of myosin kinase and Camp-dependent protein kinase in rat liver.

, Anti-HIV protease

IC50 was 5.12μM, which decreased the transport of Ca2 + -ATPase and Ca2 + in skeletal muscle sarcoplasmic reticulum in a dose-dependent manner.

Purity: HPLC & gt; 98%

CAS: 6147-11-1

Molecular weight: 410.59 g / mol

Molecular formula: C24H26O6


Specification

Type:Monomer plant

Form:Powder, Brown powder

Part:Fruit

Extraction Type:Solvent Extraction

Packaging:Carton, aluminiu foil bag inside

Place of Origin:Shaanxi, China (Mainland), Shaanxi,China(Mainland)

Grade:Grade

Model Number:Monomer plant

Product Name:Mangostin

Cas number:6147-11-1

Specification:98%

Test method:HPLC

Molecular Formula:C24H26O6

Molecular weight:410.47

Shelf life:2 Years



Extraction Process

Mangosteen extract Garcinia angustifolia Mangosteen as the raw material extraction active ingredients, containing xanthones, phenolic acids, anthocyanins, polymer tannic acid and other ingredients. Has good antioxidant activity, antibacterial, anti-inflammatory and anti-allergy effect

The fresh mangosteen peel was dried and pulverized 6.4 kg, and then extracted with 95% ethanol 3 times for 2 hours, and the combined extract was concentrated under reduced pressure to obtain mangosteen peel extract.

854g fresh mangosteen pulp was extracted with 95% ethanol, then distilled water was extracted 3 times, each time for 2h, then distilled water was extracted and concentrated under reduced pressure to obtain mangosteen pulp extract.



Faq

1. What inhibitors of bacteria can be inhibited?

Mangosteen extract on the nature of a variety of pathogenic microorganisms have a strong inhibitory effect. Can inhibit the dermatology common pathogens - Staphylococcus aureus growth, some of which components of methicillin-resistant Staphylococcus aureus also has an inhibitory effect. Mangosteen polysaccharide extract can stimulate phagocytic cells to kill intestinal bacteria Salmonella intracellular bacteria, stimulating white blood cells play a phagocytic, bactericidal effect.

2. Is there an anti-allergy effect?

The anti-inflammatory activities of the two flavonoids extracted from mangosteen, α, γ-tumbling elements, can significantly inhibit the nitric oxide production of the RAW264.7 cell line stimulated by lipopolysaccharide and dinoprostone Products and nitric oxide synthase expression. It has been suggested that the reduction of dinoprostone levels by both substances is achieved primarily by inhibition of cyclooxygenase 2 activity and nitric oxide production. In the model of paw edema induced by carrageenan injection, the inhibitory effect was found after treatment with α-tramadol for 3 hours. Γ-down twist son can inhibit the synthesis of prostaglandin nerve cells in rats. Therefore, these two substances have a good anti-inflammatory effect, can be used as anti-inflammatory drug development of precursor compounds. Studies have shown that 40% ethanol extract on immunoglobulin E-mediated RBL-2H3 cells have a strong inhibitory effect on histamine release. In addition, the passive skin allergic reaction was also significantly inhibited, indicating mangosteen extract has good anti-histamine and anti-allergic skin

3. Whether the role of cancer cells?

Mangosteen extract also enhance the body's immune function, and a variety of human tumor proliferation has a good inhibitory effect. Mangosteen polysaccharide has a phagocytic cell-like intracellular killing activity, involved in human immune function. Garcinia flavonoids E has strong cytotoxic effects on various liver cancer cell lines, as well as a number of gastric cancer and lung cancer cell lines.