100% Natural Birch Bark Extract, Birch Bark Extract powder, Betulinic acid 70% 98%/CAS no. 472-15-1 supplier,factory,price

Company Details

  • Xi'an Yuanyu Biological Co., Ltd.

  •  [Shaanxi,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , East Europe , Europe , Middle East , North Europe , Oceania , Other Markets , West Europe , Worldwide
  • Exporter:91% - 100%
  • Certs:ISO9001, FDA
  • Description:Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

Xi'an B-Thriving I/E Co.,Ltd.

Plant Extracts manufacturer / supplier, offering Natural Sweeteners,Herbal Extracts, etc.

100% Natural Birch Bark Extract, Birch Bark Extract powder, Betulinic acid 70% 98%/CAS no. 472-15-1

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    Payment Type: L/C,T/T,D/P,Money Gram,Western Union
    Terms of Trade: FOB,CIF,FCA
    Min. Order: 1 Kilogram
    Delivery Time: 7 Days

Basic Info

Product Description

Product Name:White Birch Bark Extract

Betulin 80%, 90%, 95%, 98% by HPLC
Betulinic acid 70%, 80%, 90%, 95%, 98% by HPLC
Botanical source:Betula Platyphylla
Appearance:White crystaline Powder
Melting Point:303 - 306 °C
Molecular Formula:C30H48O3
Molecular Weight:456.71
CAS No.:472-15-1

Main Function

1.Betulinhelps facilitate the excretion of fluids and promote metabolic activity.
2. Betulin is used for preventing hyperlipidosis ,Prostaglandin-Synthesis-Inhibitor
3.Betulincan anti-tumor, betulin orally to treat their gout, rheumatism and kidney stones. Besides,most people use betulin in one of four ways: as an infusion, decoction, extract or tincture.
4.Betulinsanti-inflammatory and skin soothing abilities are often used to treat eczema, psoriasis and warts.
5.Betulincan be used as adaptogenic, betulin is used to refer to a natural herb product that increases the body's resistance to stress, trauma, anxiety and fatigue.
6. Betulin is effect on anti-oxidant.Since betulin contains vitamins B1, B2, A, C and E, betulin is also believed to work as an antioxidant capable of slowing or preventing the oxidation of other molecules.
White birch bark extract/Betulin 50%-98%/Betulinic acid 98% White birch bark extract/Betulin 50%-98%/Betulinic acid 98%

Application

Food supplement
Birch bark has been shown to act as a laxative and diuretic, and many consume it orally to treat their gout, rheumatism and kidney stones. In fact, one of the plant’s chemical components, Betulinic Acid, is currently being tested as a promising cancer treatment. The water soluble form of the acid inhibited the growth of human prostate cancer cells by nearly 96%, according to a Weill Cornell research team. Some researchers believe that it has the ability to destroy tumor cells and slow the growth of both HIV and melanoma.
Cosmetics
With regards to skincare, it’s often administered as a natural medicinal treatment because it helps facilitate the excretion of fluids and promote metabolic activity. Its anti-inflammatory and skin soothing abilities are often used to treat eczema, psoriasis and warts. Since it conatins vitamins B1, B2, A, C and E, it is also believed to work as an antioxidant. Most people use it in one of four ways: As an infusion, decoction, extract or tincture

Why Choose UsCompany InformationCompany InformationWuxi AccoBio Biotech Inc. is located in the beautiful city of Wuxi, Jiangsu Province. We pride ourselves on being the professional supplier & manufacturer of an extensive range of high quality health/lifestyle/sports nutritional raw materials, APIs and fine chemicals. It helps Nutritional Supplements and Pharmaceutical Industry to provide extensive products for sports nutrition & healthy living as well as helps the clients' purchasing work easier and more cost-saving.
We believe that quality is the life of a company. All the products and raw materials manufactured and sourced in AccoBio are in strict accordance with ISO9001: 2000 quality management system. We promise you the guaranteed quality and value of all our products. To be an attractive partner to our customers, we focus on the innovative chemicals and good service solutions.
AccoBio has been pursuing the management idea of "based on people", constructing a strong talented team and trying our best to fulfill almost all the customers' requirement. Our goal is to become a global, professional and reliable company that supplies international customers with best products and service. We will welcome all the customers from both inland and abroad with cautious and enthusiastic service. We are trying to build the eastern brand of regarding the quality and credit, and we hope AccoBio's development will make even greater contributions to the development of science research and human's health industry.

Quality Control of Health Sources
1. A system in accordance with GMP standard, supervision on whole production process-
2. Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the detailed Certificate of Analysis
3. Procurement-Strictly on selecting raw materials
4. Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc pharmaceutical and/or food standards
5. Warehousing and storage: Clear and dry condition with suitable temperature.
6.Transportation - Audit and supervise the logistics environment to ensure storage safety
7. Keep samples for all batches goods to be traceable in case of quality discrepance.

What is ISO 9001:2008?
ISO stands for International Standards Organization. The "9001:2008" designation is the specific standard under which our Quality Management System is certified. Since 2003, Wuxi AccoBio Biotech Inc. has successfully implemented a quality system in accordance with the requirements of ISO 9001:2008 quality standard for custom packaging of essential oils, natural cosmetics and their raw materials. We are audited each year to International Standards by Certified auditors. They ensure that our system conforms; specifically we are required to meet the following obligations: Annual Customer Service survey Every customer concern must be logged and trended The Management Team must meet monthly with documented meeting notes All approved vendors must be listed and gone through appropriate screening Internal audits must take place each quarter We must demonstrate objective evidence of improvement We must have written processes and procedures for the following:
•Defining Management Responsibilities
•Defining Training requirements and responsibilities
•Establishing and Evaluating Quality Vendors
•Control of Product
•Control of Non-conforming product
•Production planning
•Calibration and testing of equipment
•Inspection and acceptance criteria
•Purchasing and receiving
•Identify business elements that can affect quality
•Documentation and record keeping
•Master list of approved forms
•Traceability from purchase through to end user
•Verification and storage of product
•Effective handling and packaging
•Analysis of data
Pleaseclick hereto download a copy of our ISO 9001:2008 registration.
What is an MSDS?
MSDS stands for Material Safety Data Sheet. It provides detailed product information needed by material handlers and emergency workers on physical and chemical data. This includes melting points, boiling points, flash points, reactivity, first aid instruction, toxicity, storage recommendations, disposal instructions, control measures, protective equipment instructions, and spill and leak procedures.
What is a Certificate of Analysis?
A Certificate of Analysis is the result of testing against acceptable parameters. Certificates of Analysis can look quite different from product to product, industry to industry. However, with Essential Oils, measurement quite often consists of the dominant constituent of a particular oil.
Quality Assurance

Quality Assurance laboratory is well designed as per pharma standards having chemical and microbiological sections, apart from instrumentation room. All sections have latest testing instruments, which are handled by qualified and experience technical personnel assuring the quality of in put raw material and final products as per laid down specifications. In process control ( IPC ) tests are carried out at specified stage of processes to conform that quality standards are met .AccoBio Quality Assurance team monitors the quality of the products right from the raw materials procurement stage to the expiry date of the finished product, thus ensuring the customers get the finest products.In order to insure the quality,AccoBio control raw material strictly. All the products should be record with all the procedure so that we can check each step easily.
Lab equipment:
• HPLC
• ECD-GC
• UV-VIS Spectrophotometer

Equipment introduction:
• 4 sets of 6 M3 multifunctional stainless extracting tank
• 4 sets of 1.5MT stainless external reflux combination
• 1 set of 2.4MT dual-action falling-film evaporator
• 4 sets of glass lining reaction vessel
• 6 sets of 350*1500 PE chromatographic column
• 250 vertical spray drying tower
Productionprocedure is according to GMPstandard strictly to ensure the uniformity and stability of our products.

OEM Service

Softgel
AccoBio has specialized in providing Natural Products Industry with premium quality dietary supplements in capsule. Drawing on years of experience and successful outcomes ,we are adept at offering our customers tailor solutions that precisely address their specific needs. You can count on us to effectively meet your needs in a reliable manner.
Hard capsules
AccoBio has chosen the particular gelatin, equipped with High Airflow Particulate Air (HAPA)filer system, and strict temperature and humidity-controlled environment ensure the stability of powder drugs. And taking into account the vegetarian, special religious needs of consumers, we also developed a capsule of pure plant production process. AccoBio capsules can be imprinted with useful information as: logo, product name, company or even dosage details.
Whatever your business goals and whichever format your products ultimately takes, AccoBio has greater capabilities to meet your need than any other companies.
Pre-Mix Service
AccoBio one-stop nutrients premix solution offer expert experiences in food and supplements. AccoBio could not only provide you with vitamin premix, but also amino acid, minerals, carotenoids and herbal extract premix.
Product Range
PreMix-Vitamins
PreMix -Amino Acids
PreMix -Minerals
PreMix -Carotenoids
PreMix -Herbal Extracts
Application
-Infant & child functional food
-Cheese
-Dairy
-Sports Beverage
-Functional Drink

Introduction

"Introduction:      
    Birch bark has been shown to act as a laxative and diuretic, and many consume it orally to treat their gout, rheumatism and kidney stones. In fact, one of the plant’s chemical components, Betulinic acid, is currently being tested as a promising cancer treatment. The water soluble form of the acid inhibited the growth of human prostate cancer cells by nearly 96%, according to a Weill Cornell research team. Some researchers believe that it has the ability to destroy tumor cells and slow the growth of both HIV and melanoma.
 
    The birch bark extract is a healing extract, which for centuries was used in treatment and in a life; it is organic, balanced natural combination of various curative natural connections - Betuline, Betulinic acid, Lupeol, etc.
 

   Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name.It is manufactured from raw matertial betulin by chemical synthesis. Betulinic acid has the anti-inflammatory, anti-virus, anti-tumor,cholagogic function and liver protective effect.It can also promote human body metabolism. As a kind of biologics, betulinic acid has the curative effect in anti-HIV, cancer and human melanoma cell without killing healthy cells. According to the recent research, it has the inhibiting effect on cerebroma,neuroectodermal tumor, leukemia and other malignant cells."


Active ingredients

"Natural Compounds

Catalog Number473-98-3

The birch bark extract is extracted from the bark of birch. The main active ingredient is betulin. It has the functions of anti-inflammatory, anti-virus, inhibiting the dissolution of protein in hair fiber, improving damaged hair and promoting hair growth. It can be applied to food, Cosmetics and pharmaceutical industries


Specification

Specifications

Type:White Birch Extract

Form:Powder

Part:Bark

Extraction Type:Solvent Extraction

Packaging:Drum, Plastic Container, Vacuum Packed

Place of Origin:Zhejiang, China (Mainland)

Grade:First Grade

Brand Name:Boten

Model Number:BT-WBE

Latin Name:Betula platyphylla

Active Ingredients:Betulin/Betulinic acid

Color:White powder

Appearance:Fine Powder

Odor:Characteristic

Size:100% pass 80 mesh

Specification:Betulin 80%,90%,98% Betulinic acid 50%,90%,95%,98%

Test Method:HPLC

Sample:Free Sample

Shelf life:2 Years


Extraction Process

500g of dry birch (ifeiw / a P IatyphyI la Suk) bark was extracted with 5 times of 80% methanol and refluxed for 3 times. Each time the mixture was refluxed for 60min, the extracts were combined and the methanol was recovered Liquid, into the step-open container placed in the heating volatile methanol, let cool, add I times the amount of water, the precipitation of a large number of precipitates, extract the concentrate by suction; concentrate with 2 times the amount of water transferred into suspension, I times the amount of methylene chloride extraction 3 times, the combined extract, vacuum recovery of methylene chloride concentration, to more difficult to concentrate, placed in an open container heating as much as possible to play Nini methyl chloride, let cool, dry; After 200-300 mesh silica gel column chromatography, first with 1-2 times the amount of hexane as the mobile phase elution, followed by 3-5 times the amount of methylene chloride and methanol 10: 1 elution ratio elution, The eluate was collected, concentrated under reduced pressure at room temperature, and dried to obtain 37. 2 g of the extract of the present invention. The content of lupeol in the inventive extract was 22.18% by HPLC.


Faq

Q1: What's the main order for the usual?

  For the hight value product min order starts from 1g and generally starts from 10g.

 

Q2: What's  the sample cost?

  Generally free sample could be oferred except the high value product.

 

Q3: What's the package and payment terms?

  Our package:  in 2 plastic bags, Aluminum foil bag outside, 1-10kg /carton, 10-25kg /drum.

  Payment: T/T, L/C, could be through Paypal, Escrow, West  Union.